The simple, flexible Clinical Trial Management System (CTMS).

Smart Study Management!

SimpleCTMS is a Clinical Trial Management System (CTMS) for Sponsors & CROs. 

A fresh, easy to use web application. Flexible and affordable solutions. Amazing customer support.


Scalable and Cost Effective Clinical Study Solutions

SimpleCTMS was designed and developed to offer the benefits of a CTMS (Clinical Trial Management System) without the extensive upfront financial and resource commitments associated with traditional enterprise systems or the inherent inefficiencies of worksheet trackers.
SimpleCTMS provides early stage drug developers a scalable and cost effective solution to improve the management, performance and study startup costs associated with clinical trials.

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  • Easy to use, flexible, customizable
  • Runs in standard web browsers
  • Supports large, interdisciplinary global teams or small studies and teams
  • Portable for future studies
  • Well defined user groups
  • One system for both blinded and unblinded user types
  • Multi-study and portfolio management 
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  • Supports 21 Part 11
  • Secure cloud hosting in the US available from a validated hosting provider.
  • Designed by clinical experts, built by technology experts.
  • Backed by a quality system using validated software processes.
  • Software-as-a-Service model includes monitoring and maintenance.
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  • A dedicated client manager provides pro-active support and guidance.
  • All users receive technical support from our team of clinical software experts.
  • Online video training.
  • Customized training and professional services are available at additional cost.
  • System enhancements and updates are included.

See Our Cover Story in PharmaTech Outlook!

The March 2017 issue of PharmaTech Outlook features Trial By Fire Solutions' approach to transparency and affordability for CTMS. We are proud to be leveling the playing field for all clinical teams!

See our cover story here!

See Trial By Fire Solutions at the Following Events!

SCOPE Conference
February 18–19, 2020
Hyatt Regency Orlando
Orlando, FL
Booth #421

DIA 2020 Annual Meeting
June 15-17, 2020
Walter E. Washington Convention Center
Washington, DC
Booth # 1010

Trial By Fire Clinical Software is Simplifying Studies Around the Globe


CROs utilize our products


Sponsors utilize our products


Countries utilize our products


Integrations with eClinical vendors


Studies managed across
15,000+ sites & 50,000+ subjects


Electronic Visit Reports Authored


What People Are Saying About SimpleCTMS!

Very Responsive and Knowledgable

We are extremely pleased with the SimpleCTMS customer support and find the client managers and technical team to be very responsive and knowledgeable.  We highly recommend SimpleCTMS!” 

Chad Orevillo, MPH
Vice President and Head of Clinical Operations
Pearl Therapeutics

Easy To Use and Adopt

SimpleCTMS is easy to use, easy to adopt, and their customer support and willingness to assist is phenomenal

Head of Clinical Operations
Spectrum Pharmaceuticals

Top Notch Customer Service

SimpleCTMS is easy to use and supports ‘real-world’ clinical operations. From set-up to close-out, the SimpleCTMS team is always there to guide and provide support. The system is superb and the customer service is top-notch.” 

Senior Partner


Looking for More?

Our SimpleTrials Product is an on-demand subscription based CTMS for Sponsors, CROs and Sites.
Plans start at $124/month with no long-term commitment.

White Papers

These white papers (available for download)
are a must-read for any organization
considering clinical trial management system adoption.  

True Cost of CTMS Report

Questions to ask your eClinical Provider